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Estrogen flips testosterone gene switch.(research indicates estrogen can bind to male hormone receptor)(Brief Article)
Science News
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May 16, 1998|
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COPYRIGHT 1998 Science Service, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
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Talk about an odd couple. A new study suggests that estrogen, frequently considered the quintessential female hormone, can turn on genes by binding to the same protein that responds to testosterone and other androgens, the so-called male hormones.
This unexpected union only activates genes in the presence of a matchmaker protein called [ARA.sub.70], however, reports a research group led by Chawnshang Chang of the University of Rochester (N.Y). He and his colleagues describe their study in the May 12 Proceedings of the National Academy of Sciences.
The ...
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