Found: mouse circadian rhythm gene. From: Science News | Date: May 17, 1997| Author: | COPYRIGHT 1997 Science Service, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

Researchers led by John Takahashi have identified a gene called clock that can disrupt circadian rhythms in mice when mutated. The gene is active in the brain and in many other tissues, where it may have non-circadian functions.

Never trust a mouse from Joseph S. Takahashi's laboratory to be on time. A few years ago, Takahashi and his colleagues randomly mutated genes in mice to disrupt their biological clock, the internal timepiece that creates daily cycles, or circadian rhythms, of activities such as sleeping, eating, and exploring.

Takahashi's group succeeded in creating mice ...

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