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DNA cleavage in vitro by DNA topoisomerase II in the AF4 Gene translocation breakpoint region.(COMMUNICATIONS--UNDERGRADUATE)
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Objective: The mixed-lineage leukemia gene, (MLL), fuses to one of >50 different translocation partner genes in several subtypes of de novo human acute leukemia. All breaks in MLL occur within the same 8 kilobase (kb) region, (bcr). The most prevalent MLL translocation partner is AF4. MLL fusions are also observed chemotherapy-related, secondary leukemias. These MLL fusions often follow treatment with drugs which interfere with DNA topoisomerase II (topo II) activity and implicate topo II in the translocation mechanism, in vivo.
In vitro studies show the MLL 8 kb ...
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Cardiff Software Enhances and Expands Reseller Programs; Opens Six Regional Support Offices to Champion VARs and Integrators.
PR Newswire
; ...Sales Support, Seminars and Resources to Cardiff Reseller Partners - SAN DIEGO, Jan. 8 /PRNewswire/ -- Cardiff Software, Inc., a leading supplier...company is enhancing and expanding the Cardiff Certified Platinum Reseller Program...
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Cardiff Software Appoints Mike Flanagan as Director of America's Channel Sales; - 12-Year Industry Veteran and Former Vignette and Symantec Executive to Be Formally Introduced at Cardiff's Ninth Annual Reseller Conference, Connections 2003, on February 9 -.
PR Newswire
; ...SAN DIEGO, Feb. 4 /PRNewswire/ -- Cardiff Software Inc., a leading global provider...developing and expanding revenues for Cardiff's OneSource channel partner program...successfully resell, implement and support Cardiff's products across the globe. Flanagan...
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Cardiff Software Europe Exceeds Growth Targets, Accelerates Planned Expansion with Opening of Cardiff Germany 6 Months Early.
PR Newswire
; - Cardiff Germany Names Ulrich Michelberger Managing Director; Signs...Reseller in Europe - SAN DIEGO, Sept. 13 /PRNewswire/ -- Cardiff Software, Inc. today announced that Cardiff Europe has exceeded growth projections in its first 6 months...
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Cardiff Software Named Fastest Growing Data and Document Capture Vendor; Over 20,000 Choose Cardiff.
PR Newswire
; - Cardiff Software Grows 449% in Just Five Years...Calif., Sept. 16 /PRNewswire/ -- Cardiff Software, Inc. today announced that company...Deloitte & Touche, which has named Cardiff to the "Technology Fast 50," a list...
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Autonomy Cardiff Leads in Support of New NAVA STP Standards Initiative.
PR Newswire
; Cardiff Offers Industry-First Integrated Solutions...June 4 /PRNewswire-FirstCall/ -- Cardiff, a division of Autonomy Corporation plc...annuities and insured retirement solutions, Cardiff has actively participated in the development...
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Cardiff Releases New Version of MEDIclaim Option for TELEform v8.1; - Cardiff TELEform MEDIclaim Option Features Improved Recognition and System Automation for the Rapid and Efficient Processing of All Standardized U.S. Medical Claim Forms -.
PR Newswire
; Cardiff Software, Inc., a leading global provider...announced the immediate availability of Cardiff TELEform(TM) v8.1 MEDIclaim Option...complete list please visit http://www.cardiff.com/MEDIclaim/new_features.asp...
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Cardiff LiquidOffice(TM) Selected By the Office of the Inspector General, U.S. Department of Labor; - Office of the Inspector General to Update Internal IT and HR Form-Driven Processes With LiquidOffice's Proven eForm Technology -.
PR Newswire
; SAN DIEGO -- Cardiff Software Inc., a leading global provider...Department of Labor, has selected the Cardiff LiquidOffice(TM) eForm management...the Inspector General's selection of Cardiff LiquidOffice further validates the escalating...
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Cardiff spoil the feel-good factor as Edinburgh come up short Fringe players get a workout but unbeaten run ends
Newspaper article from: The Scotsman
; Edinburgh 13 Cardiff 23 EDINBURGH'S unbeaten home run came...disappointing end at Murrayfield last night when Cardiff edged a battle of two under- strength...missing eight first-choice players and Cardiff six internationals and suspended prop...
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 "Western Mail (Cardiff, Wales)")
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Cardiff fans get most bans; Soccer hooliganism figures put City at top of league with 169 barred from matches.(News)
Newspaper article from: Western Mail (Cardiff, Wales)
; Byline: Rhodri Evans CARDIFF City has been awarded the unwanted spot...the end of last month a total of 169 Cardiff fans had been banned from football grounds...Since the figures were collated another Cardiff City fan, former club employee Neil...
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Cardiff LiquidOffice(TM) eForm Management System Selected by County Of Santa Clara to Automate Forms and Business Processes; - Flexibility and Easy Integration With BEA and Vignette Among Deciding Factors; LiquidOffice Routes, Tracks and Processes Forms via Web-Based Management System -.
PR Newswire
; SAN DIEGO -- Cardiff Software Inc., a leading global provider...their community," said Dan Shirra, Cardiff's vice president of worldwide marketing...their business-critical processes. Cardiff's open systems approach also allows...
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