Novel therapeutics for schizophrenia: targeting glycine modulation of NMDA receptors.(Essential PsychopharmaSTAHLogy)(N-methyl-d-aspartate)(Report)

Psychopharmacology Educational Updates (PsychEd Up) | November 1, 2007| | Copyright

Issue The pathophysiology of schizophrenia may involve hypofunctioning of NMDA (N-methyl-d-aspartate) receptors, which are modulated in part by actions at the glycine cotransmitter site of these receptors.

Action Understand the role of the glycine site in the functioning of NMDA receptors and identify potential methods to modulate activity at that site.

Benefit Understanding the role of the glycine site in the functioning of NMDA receptors and thus in the pathophysiology of schizophrenia is important as novel treatments targeting this site are being ...

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