New findings reported from Umea University, Umea Center for Molecular Medicine describe advances in RNA research.

Gene Therapy Weekly | January 29, 2009 | Copyright

A report, 'The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity,' is newly published data in Endocrinology. "The homeodomain transcription factor insulin promoter factor (IPF)-1/pancreatic duodenal homeobox (PDX)-1 plays a crucial role in both pancreas development and maintenance of beta-cell function. Targeted disruption of the Ipf1/Pdx1 gene in beta-cells of mice leads to overt diabetes and reduced Ipf1/Pdx1 gene expression results in decreased insulin expression and secretion," ...

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