Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes.(Research article)

BMC Genomics | November 19, 2008| | Copyright

Authors: Lokesh P Tripathi [1,2]; R Sowdhamini (corresponding author) [1]

Background

The proper functioning of a cell is facilitated by a precise regulation of protein levels, which in turn is maintained by a balance between the rates of protein synthesis and degradation. Protein degradation mediated by proteolysis is an important mechanism for recycling of the amino acids into the cellular pool and to possibly generate energy during starvation. Proteins like enzymes, transcription factors, receptors, structural proteins etc . require proteolytic ...

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