 "Hayling Islander (Hayling Island, England)")
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The [pounds sterling]1m ride nearing capacity.
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THIS year's ride, our 22nd and the last year we are planning to visit Paris or Versailles for the foreseeable future, is rapidly filling up, more so than in recent years.
The shorter 3-Day ride already has a waiting list for cancellations, since it is limited to one 53-seater coachload.
There are still a few places left on the longer 6-Day ride, but it is expected that this will be complete before Easter, although once again a waiting list will be created, in the anticipation of the inevitable cancellations, averaging 20+ riders per year - only one so far! ...
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Spontaneous Mutations in Diploid Saccharomyces cerevisiae: More Beneficial Than Expected
Magazine article from: Genetics
; ...all fitness-altering mutations are deleterious. The mutation rate was estimated as 6...spontaneously arising beneficial mutations, the genome-wide mutation rate, and the average effect of spontaneous mutations. Our study improves on...
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Mutations Linked to HBV Levels in IFN-Treated Patients.
Newspaper article from: Hepatitis Weekly
; ...determination of these two mutations and viral levels...core promoter mutation appeared to occur...induce any specific mutations. Core promoter mutation appeared to develop...of the precore mutation, and the virus with these two mutations seemed to be the...
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Mutation panel described for screening BRCA1/2 mutations in French Canadians.
Newspaper article from: Biotech Week
; ...Oros and coauthors said their "results define a new mutation panel for screening BRCA1/2 mutations and the phenotype of mutation-positive families harboring the common mutations in the French Canadian population." Oros and coauthors...
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BRAF Mutations in Melanocytic Lesions and Papillary Thyroid Carcinoma Samples Identified Using Melting Curve Analysis of Polymerase Chain Reaction Products
Magazine article from: Archives of Pathology & Laboratory Medicine
; ...Forty different mutations have been identified...with the T1799A mutation leading to substitution...than 90% of the mutations.3,5-11 The V600E mutation is within the...as a BRAF K601E mutation.28 Interestingly, BRAF mutations do not seem to...
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Mutations in K-ras Codon 12 Detected in Plasma DNA Are Not an Indicator of Disease in Patients with Non-Small Cell Lung Cancer
Magazine article from: Clinical Chemistry
; ...significantly to mutation detection (in their case, K-ras mutations in the plasma of...note that K-ras mutations have been detected...observed K-ras mutation in 2 volunteers...the detection of mutations in codon 12 of...
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Cystic fibrosis mutations and associated haplotypes in Turkish cystic fibrosis patients
Magazine article from: Human Biology
; ...associated with unknown mutations. The mutation spectrum of CF in...TURKISH POPULATION, MUTATION SCREENING, HAPLOTYPES Mutations in the cystic fibrosis...of unidentified mutations. In populations...heterogeneity, mutation analysis can be...
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Adaptive Mutation in Saccharomyces cerevisiae
Magazine article from: Critical Reviews in Biochemistry and Molecular Biology
; ...selection-induced mutations, replication-independent...starvation, spontaneous mutation 1. INTRODUCTION...stationary-phase mutations (e.g., Ryan...the benefit of the mutations. In contrast, "adaptive mutation" (Steele and Jinks...
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Mutation Rate Variation at Human Dinucleotide Microsatellites
Magazine article from: Genetics
; ...locus, even though their mutation rates are several orders of...Furthermore, the estimates of mutation rates with direct methods...of the observed number of mutations over several loci, scored...reasonable estimates of the average mutation rate of a group of microsatellite...
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MUTATIONS OF THE NOGGIN AND OF THE ACTIVIN A TYPE I RECEPTOR GENES IN FIBRODYSPLASIA OSSIFICANS PROGRESSIVA (FOP)
Magazine article from: Genetic Counseling
; ...4), for mutations in the noggin...and for the mutation 617A in the...and the 271T mutations (in s2, s3...and the 283A mutation in f7/FRA2...of the M)G mutations usually don't bear the 617A mutation of the ACVRl...
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Mutations in melanocortin 4 receptor gene linked to binge-eating behavior.
Newspaper article from: Genomics & Genetics Weekly
; ...association was found between mutations in the leptin-binding region...of the subjects possessed mutations in the region of POMC that...characteristic of subjects with a mutation in MC4R, a candidate gene...melanocortin 4 receptor gene mutations. New England Journal of Medicine...
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