Atypical evening cortisol profile induces visual recognition memory deficit in healthy human subjects.(Research)

Molecular Brain | August 21, 2008| | Copyright

Authors: Heather Gilpin [1,2]; Daniel Whitcomb [2,3]; Kwangwook Cho (corresponding author) [1,2,3]

Background

Cortisol levels are maximal in the early morning and minimal in the late evening in humans [1, 2, 3]. Dysregulation in the diurnal cortisol rhythm has been associated with depression and pathological aging [4, 5]. For example, age-dependent increases in evening cortisol levels have been reported in healthy subjects [6, 7, 8]. The study [6] also found a phase advance in the morning acrophase in the aged subject group. In addition, nocturnal ...

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