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Sick of it all. (Multiple chemical sensitivity sufferers)
Reason
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June 1, 1996|
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COPYRIGHT 1996 Reason Foundation. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
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PEOPLE WITH "MULTIPLE CHEMICAL SENSITIVITY" ARE DEFINITELY SUFFERING. THE QUESTION IS, WHY?
Karen was the librarian at a newspaper in Los Angeles where I worked. When we moved to new offices, somebody told her the library's bookshelves contained formaldehyde. Soon she was suffering from a headache, aching joints, and labored breathing. But then Karen heard there was no formaldehyde in the shelves. Suddenly the symptoms disappeared. A colleague later told me that it turned out the shelves contained formaldehyde after all, but Karen remained blissfully ignorant of this ...
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Myosin Cross-Bridge Kinetics and the Mechanism of Catch
Magazine article from: Biophysical Journal
; ...twitchin. The kinetic parameters of myosin cross-bridge turnover in permeabilized...determined by single turnover measurements on myosin-bound ADP. Under isometric conditions...Also, there is no measurable turnover of myosin-bound ADP during relaxation of catch...
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Myosin I contributes to the generation of resting cortical tension
Magazine article from: Biophysical Journal
; ABSTRACT The amoeboid myosin I's are required for cellular cortical functions...the actin-filled cortex of various Dictyostelium myosin I mutants. Given that the amoeboid myosin I's possess both actin- and membrane-binding domains...
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Myosin isoform shift does not significantly contribute to contractile deficit.
Newspaper article from: Clinical Trials Week
; ...NewsRx.com & NewsRx.net) -- Myosin isoform shift does not significantly contribute...In non-failing human myocardium, V1 myosin comprises a small amount (<10%) of the total myosin content, whereas end-stage failing hearts...
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Myosin-Vb functions as a dynamic tether for peripheral endocytic compartments during transferrin trafficking.(Research article)
Magazine article from: BMC Cell Biology
; ...for unconventional myosins in higher eukaryotes...have shown that many myosin head domains bind...by unconventional myosins in a cellular context...to reposition the myosin in the absence or...to unconventional myosins, allowing us to...sensitized mutant myosin to actin by ...
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Myosin XI-K Is Required for Rapid Trafficking of Golgi Stacks, Peroxisomes, and Mitochondria in Leaf Cells of Nicotiana benthamiana1[W][OA]
Magazine article from: Plant Physiology
; ...of the tested six myosins appears to be involved...strongly suggest that myosin XI-K has a major...peroxisomes, whereas myosins XI-2 and XI-F...the identity of the myosin(s) involved remains unknown. Myosins are conserved molecular...
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Cardiac Myosin-Binding Protein C Modulates the Tuning of the Molecular Motor in the Heart
Magazine article from: Biophysical Journal
; ABSTRACT Cardiac myosin binding protein C (cMyBP-C) is an...contractility. Its precise effect on myosin cross-bridges (CBs) remains unclear...Huxley's equations. The probability of myosin being weakly bound to actin was higher...
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Kinaris Targeting Myosins with Allosteric Inhibitors.
Newspaper article from: BioWorld International
; ...tailored for individual myosin isoforms. Cytokinetics...Francisco, also is targeting myosins, but it is developing...In prostate cancer, myosin VI is an early marker...appears to be mediated by myosins IIA and IIB, although...disease, the role of myosin is more established...
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Two Class XI Myosins Function in Organelle Trafficking and Root Hair Development in Arabidopsis1[OA]
Magazine article from: Plant Physiology
; ...redundant nature of myosin function in plants. Myosins are signature molecular...all 13 class XI myosins of Arabidopsis to...in addition to myosin XI-K, myosin...specific to this myosin (Fig. 1C). Inactivation of Myosins XI-2 and XI...
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Multiple myosin motors and mechanoelectrical transduction by hair cells.(The Future of Aquatic Research in Space: Neurobiology, Cellular and Molecular Biology)
Magazine article from: The Biological Bulletin
; ...adaptation motors, which likely contain myosin molecules (reviewed in Hudspeth and Gillespie...prove that adaptation is carried out by myosin molecules and to identify the responsible...of the properties of skeletal-muscle myosin. We have applied general principles derived...
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Unconstrained Steps of Myosin VI Appear Longest among Known Molecular Motors
Magazine article from: Biophysical Journal
; ABSTRACT Myosin VI is a two-headed molecular...direction opposite to most other myosins. Previously, a single myosin VI molecule has been shown...Ali et al., 2002). Both myosin VI and V, like most other myosins, have two globular motor...
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