'Estrogen' pairings can increase potency. (synergistic estrogenic effects observed among the pesticides endosulfan, dieldrin and chlordanehave)(Brief Article)

From: Science News | Date: June 8, 1996| Author: | Copyright information

Toxicologist John A. McLachlan and his coworkers made a startling observation 2 years ago: A pair of polychlorinated biphenyls (PCBs) delivered together had up to 20 times the ability to switch the sex of incubating turtles as either of these weak estrogen mimics had when delivered alone (SN: 10/8/94, p. 239). Now, McLachlan and his coworkers at the Center for Bioenvironmental Research at Tulane and Xavier Universities in New Orleans note even more dramatic synergies among several ubiquitous pesticides. For instance, they had to use 160 times as much endosulfan or 1,600 times as ...

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