Research conducted at S. Sigismund and co-authors has provided new information about life sciences.(Report)

Obesity, Fitness & Wellness Week | August 30, 2008 | Copyright

New research, 'Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation,' is the subject of a report. "Clathrin-mediated endocytosis (CME) is the major pathway of epidermal growth factor receptor (EGFR) internalization. It is commonly believed that CME mediates long-term attenuation of EGFR signaling by targeting the receptor for degradation," investigators in Milan, Italy report (see also Life Sciences).

"However, the EGFR can also be internalized through (a) clathrin-independent pathway(s), and it remains unclear ...

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