Nuclei shape analysis, a statistical approach.(Report)

Image Analysis and Stereology | March 1, 2008| | Copyright

ABSTRACT

The method presented in our paper suggests the use of Functional Data Analysis (FDA) techniques in an attempt to characterise the nuclei of two types of cells: Cancer and non-cancer, based on their 2 dimensional profiles. The characteristics of the profile itself, as traced by its X and Y coordinates, their first and second derivatives, their variability and use in characterization are the main focus of this approach which is not constrained to star shaped nuclei. Findings: Principal components created from the coordinates relate to shape with significant ...

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