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A formal synthesis of (+)-muricatacin from L-tartaric acid.(GENERAL NOTES)(Report)
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Muricatacin (1) is an acetogenin that displays cytotoxic activity towards certain tumor cell lines found in humans (Figure 1). This lipid-soluble class of anticancer drug was first isolated from the seeds of the Soursop tree (Annona muricata) and has received considerable attention in recent years. This paper describes a formal synthesis of (+)-muricatacin (1) using tartaric acid (2) as a chiral controller. The key step in this synthesis is the formation of butenolide 3 by way of intramolecular cyclization of 4a while under acidic conditions. The synthesis of ...
 "Sunday Mail (Glasgow, Scotland)")
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Just ask.(Features)
Newspaper article from: Sunday Mail (Glasgow, Scotland)
; Byline: MARGRET CAMPBELL Q WHO is the Molotov cocktail named after? - Ian Shankland, by email. A WOULD you believe, a Mr Molotov? Vyacheslav Mikhailovich Molotov was a Soviet politician, diplomat and a protege...
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ASK THE GLOBE
Newspaper article from: The Boston Globe
; Q. How were Molotov cocktails named? A.K., Swampscott A. The "cocktail...fighting the Russians in 1940. After Soviet Premier Vyacheslav Mikhailovich Molotov concluded the Molotov-Ribbentrop pact in 1940 with the Germans and invaded...
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Anniversaries:11th & 12th November
Newspaper article from: The Independent - London
; Anniversaries TODAY: Births: Feodor Mikhailovich Dostoevsky, author, 1821; Paul Signac, painter...Vernon Connolly, writer and critic, 1974; Vyacheslav Mikhailovich Molotov (Skriabin), Russian leader, 1986; Eamonn...
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Anniversaries
Newspaper article from: The Independent - London
; ...Fabricius, classical scholar, 1688; Feodor Mikhailovich Dostoevsky, writer, 1821; Jean-Edouard Vuillard...James Hanley, novelist and playwright, 1985; Vyacheslav Mikhailovich Molotov (Skriabin), Russian leader, 1986; Eamonn...
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Pro-Life With an Asterisk
Newspaper article from: The Washington Post
; Vyacheslav Mikhailovich Molotov, once Stalin's foreign minister...from the public. When Stalin ordered Molotov's wife jailed and cruelly put the...to a vote of the party leadership, Molotov -- sensing a conflict of interest...
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Memory of historical meeting
Newspaper article from: China Daily
; ...Foreign Secretary Anthony Robert Eden crossed the conference room to shake hands with Vyacheslav Mikhailovich Molotov, the Soviet Foreign Minister. Molotov then introduced Eden to Zhou, and Eden and Zhou warmly shook hands. After the session...
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Behind the symbolism
Newspaper article from: Jerusalem Post
; ...his "pro-Western" Commissar for Foreign Affairs Maxim Litvinov (alias Meir Moiseevitch Wallach) with Vyacheslav Mikhailovich Molotov, who in August 1939 signed the infamous nonaggression pact with Germany's Ribbentrop. In Egypt for the...
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