Effect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl ( Ambystoma ).(Research article)

BMC Genomics | February 11, 2008| | Copyright

Authors: Robert B Page (equal contributor) [1,2]; Stephen R Voss (corresponding author) (equal contributor) [1,2]; Amy K Samuels [1,2]; Jeramiah J Smith [1,2]; Srikrishna Putta [1,2]; Christopher K Beachy [3,4]

Background

Amphibian metamorphosis is generally characterized by dramatic and conspicuous developmental changes that are necessary for larvae to function as terrestrial adults. The morphological, behavioral, and physiological changes that occur during metamorphosis are associated with increases in thyroid hormone (triiodothyronine, T 3 and ...

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