Molecular targets for tendon neoformation.(Review series)

Journal of Clinical Investigation | February 1, 2008| | Copyright

Introduction

Tendons and ligaments are bundles of parallel fibers made of dense connective tissue that play an important role in mediating normal movement and stability of joints, respectively (1), (2) (Figure 1). Tendons and ligaments are similar in structure and are usually discussed in the same context. Therefore, the term tendon neoformation in this Review relates to the regeneration of both tendons and ligaments. Injury to these structures can cause significant joint instability, resulting in injury to other tissues and the development of degenerative joint ...

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