Phosphorated calix [6] arene derivatives as an ionophore for atropine-selective membrane electrodes.(DRUG FORMULATIONS AND CLINICAL METHODS)(Report)

Journal of AOAC International | January 1, 2007| | Copyright

37,40-bis-[(diethoxy-thiophosphoryl)oxy]-5,11,17, 23,29,35-hexakis(1,1-dimethyl-ethyl)-calix[6]arene-8,39,41,42-tetrol; 37,38,39,40,41-pentakis-(diethoxythiophosphoryl)-oxy]-5,11,17,23,29,35-hexakis (1,1-dimethylethyl)-calix[6]-arene-42-ol; and 37-[(diethoxythiophosphoryl)oxy]-5,11,17,23,29,35-hexakis-(1, 1 dimethylethyl)-calix[6]arene-38,39,40, 41,42-pentol were introduced as neutral ionophores for atropine-selective electrodes. Practical Nernstian responses were found (54.3, 49.1, and 50.8 mV/decade) for polyvinyl chloride membrane electrodes incorporating these compounds. ...

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