Combination therapy vs. insulin alone in NIDDM. (non-insulin-dependent diabetes mellitus)(adapted from Diabetes Care, March 1995)(Tips from Other Journals) From: American Family Physician | Date: September 1, 1995 | COPYRIGHT 1995 American Academy of Family Physicians. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

As type II, or non--insulin-dependent, diabetes mellitus (NIDDM) progresses, many patients have deterioration in glycemic control. Several studies have addressed the issue of insulin therapy alone versus combination therapy with an oral hypoglycemic agent plus insulin for the treatment of these patients. Results from these studies have been conflicting, and optimal therapy remains controversial. Chow and colleagues compared treatment efficacy, adverse effects, acceptance of treatment and quality of life issues in patients receiving combination therapy and in those receiving insulin ...

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