Hox, Wnt, and the evolution of the primary body axis: insights from the early-divergent phyla.(Review)(Report)

The thirty-plus metazoan phyla are each characterized by a distinct "Bauplan" (or body plan; see [1, 2]). A major challenge facing evolutionary biologists lies in understanding the evolution of major animal features such as body symmetry, germ layers, body cavities, skeletal systems, and nervous systems that comprise these disparate metazoan body plans [3]. In approaching these questions, it is especially useful to consider the earliest-branching metazoan ...

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