Molecular thermometer.(Applied Highlights)(Brief article)

From: Chemistry and Industry | Date: November 12, 2007| Author: | Copyright information

A molecular thermometer has been designed which exploits the fact that the characteristic time associated with the reversible protonation reaction responsible for the fluorescent green protein blinking is strongly temperature dependent at low pH (Scheme 6) (J. Am. Chem. Soc., 129, 2007, 10302). The blinking is detected by fluorescence correlation spectroscopy, and therefore provides the means for non-invasive, spatially ...

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