Tamoxifen benefit persists 10 years, new data show: risk-benefit ratio rises after first 5 years.(Women's Health)

Internal Medicine News | January 15, 2007| | Copyright

SAN ANTONIO -- A new 10-year follow-up from a landmark clinical trial of tamoxifen for breast cancer prevention indicates that the benefit continues strongly throughout the next half decade following completion of the standard 5 years of therapy, whereas adverse events are confined to the active treatment period.

"The risk-benefit ratio improves with longer follow-up. I think this is terribly important for the overall evaluation of tamoxifen in prevention. If you get the same benefit in the second 5 years as in the first 5 years without any of the side effects, the ...

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