FDA: ibuprofen blocks aspirin's cardioprotection.(Cardiovascular Medicine)(Food and Drug Administration)

Internal Medicine News | October 1, 2006| | Copyright

Concerns that nonsteroidal anti-inflammatory drugs can interfere with aspirin's cardioprotective effects received new attention following a Food and Drug Administration warning about concomitant use of low-dose aspirin and ibuprofen.

Ibuprofen can interfere with aspirin's antiplatelet effects, according to a statement issued by the Food and Drug Administration's arm responsible for compiling adverse drug events.

"Platelet function tests suggest there is a pharmacodynamic interaction between 400 mg of ibuprofen and low-dose aspirin when they are dosed ...

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