Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral[TM] index monitor.(Research)

Critical Care | September 27, 2007| | Copyright

Authors: Sandra A Prins [1]; Matthijs de Hoog [2]; Joleen H Blok [3]; Dick Tibboel (corresponding author) [1]; Gerhard H Visser [3]

Introduction

Traumatic brain injury (TBI) and generalized convulsive status epilepticus (GCSE) are conditions that require aggressive management. Barbiturates are used to stop epileptiform activity, with the aim being to improve neurological outcome. Other effects of high barbiturate levels are reduced cerebral metabolism and blood flow, which also are favourable in the treatment of severe epilepsy [1]. Barbiturate therapy ...

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