Gene therapy in skin disease.(NEWS, VIEWS, AND REVIEWS)

From: Journal of Drugs in Dermatology | Date: October 1, 2007| Author: Brownell, Isaac; Zahid, Sarwar | Copyright information

Gene therapy holds great promise for the treatment of many dermatologic diseases. (1-4) However, practical application of gene delivery has proven to be challenging. Numerous hurdles must be overcome if gene therapy is to become a viable treatment. Vector efficiency, mode of delivery, and side effects are among the leading concerns. Some highly publicized adverse events have prompted increased caution when starting human trials. These include the 1999 death of a patient after injec...

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