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Take a breather: Cath O'Driscoll goes in search of the perfect crystals for inhaled therapies by drawing inspiration from giant puffball mushrooms and ultrasound.(Fine chemicals)
Chemistry and Industry
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September 10, 2007|
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COPYRIGHT 2007 Society of Chemical Industry. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
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Rob Price can never resist the opportunity to tap a giant puffball mushroom on the rare occasions that he sees one. Watching the fungus release its clouds of trillions of spores is a perfect demonstration of how to disperse tiny micronsize particles with maximum effect, says the UK University of Bath pharmacology expert. As a model for the delivery of inhaled drugs, they don't come much better than this.
[ILLUSTRATION OMITTED]
Sadly, most inhaled drugs don't behave anything like puffball spores. 'Most inhaled drug formulations are pretty inefficient--with only 15-20% of ...
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