Evolutionary history and functional implications of protein domains and their combinations in eukaryotes.(Research)

Protein domains are the basic building blocks that determine the structure and function of proteins, and they may be considered the units of protein evolution. Furthermore, combinations of protein domains provide a broad spectrum for potential protein function [1, 2, 3, 4]. Eukaryotic genome sequencing projects have revealed complicated and varied domain architectures [5]. In particular, the number of domains in a ...

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