A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE).(Research article)(Report)

BMC Developmental Biology | August 2, 2007| | Copyright

Authors: Juan Hou [1]; Anita M Charters [2]; Sam C Lee [1]; Yongjun Zhao [2]; Mona K Wu [1]; Steven JM Jones [2,3]; Marco A Marra [2,3]; Pamela A Hoodless (corresponding author) [1,3,4]

Background

The definitive endoderm (DE) is a population of multi-potent stem cells allocated as one of the primary germ layers during gastrulation. Initially formed as an epithelial sheet of approximately 500-1000 cells around the distal cup of an E7.5 mouse embryo, the DE is rapidly organized into a tube that runs along the anterior-posterior axis of the embryo [1, 2, ...

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