Extract of Pelargonium sidoides (EPs[R] 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in vitro.

From: Phytomedicine: International Journal of Phytotherapy &Phytopharmacology | Date: February 1, 2007| Author: | Copyright information

Abstract

Clinical data show that EPs[R] 7630, an aqueous ethanolic extract from the roots of Pelargonium sidoides, can be used for the treatment of upper respiratory tract infections (URTI). The biological effects of the preparation have not been fully investigated. The objective of this study was to examine the impact of EPs[R] 7630 on the activity of human peripheral blood phagocytes (PBP).

A whole blood-based, flow cytometric assay was used to simultaneously assess phagocytosis and oxidative burst. Calcein-AM stained Candida albicans (DSM 1386) were used as target ...

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