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Lessons learned from research with chloroform.
Journal of Environmental Health
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September 1, 1994
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COPYRIGHT 1994 National Environmental Health Association. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
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New scientific evidence from the Chemical Industry Institute of Toxicology (CIIT) shows that the ability of chloroform to produce liver cancer in mice is secondary to a continual state of tissue damage and repair, produced when the chemical is given daily in large toxic doses over the lifetime of the animal. These findings suggest the need for significant changes in the design, conduct, and interpretation of animal cancer studies.
Chloroform is produced in trace amounts in the process of chlorinating drinking water [in the range of 1 to 50 parts per billion (ppb)]. It ...
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