Gene expression changes related to endocrine function and decline in reproduction in fathead minnow (Pimephales promelas) after dietary methylmercury exposure.(Research)

From: Environmental Health Perspectives | Date: September 1, 2006| Author: Carvan, Michael J.; Drevnick, Paul; Klaper, Rebecca; Rees, Christopher B.; Sandheinrich, Mark; Weber, Daniel | Copyright information

BACKGROUND: Methylmercury (MeHg) is a known neurotoxic agent, but the mechanisms by which MeHg may act on reproductive pathways are relatively unknown. Several studies have indicated potential changes in hormone levels as well as declines in vertebrates with increasing dietary MeHg exposure.

OBJECTIVES: The purpose of this study was to identify alterations in gene expression associated with MeHg exposure, specifically those associated with previously observed changes in ...

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