Periplaneta americana arginine kinase as a major cockroach allergen among Thai patients with major cockroach allergies.(Research)
From: Environmental Health Perspectives
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Date: 6/1/2006
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Author: Bunnag, Chaweewan; Chaicumpa, Wanpen; Ramasoota, Pongrama; Sakolvaree, Yuwaporn; Sookrung, Nitat; Tapchaisri, Pramuan; Tongtawe, Pongsri; Tungtrongchitr, Anchalee; Vichyanond, Pakit
Periplaneta americana is the predominant cockroach (CR) species and a major source of indoor allergens in Thailand. Nevertheless, data on the nature and molecular characteristics of its allergenic components are rare. We conducted this study to identify and characterize the P. americana allergenic protein. A random heptapeptide phage display library and monoclonal antibody (MAb) specific to a the P. americana component previously shown to be an allergenic molecule were used to ...
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