Hemisphere-specific effects of subthalamic nucleus deep brain stimulation on speaking rate and articulatory accuracy of syllable repetitions in Parkinson's disease.

From: Journal of Medical Speech - Language Pathology | Date: December 1, 2006| Author: | Copyright information

This study tested the hypothesis that left versus right deep brain stimulation (DBS) of the subthalamic nucleus (STN) would have differential effects on speech. Twenty right-handed individuals with advanced Parkinson's disease (PD) underwent unilateral STN DBS. Ten were operated on the right and 10 on the left hemisphere as indicated by severity of nonspeech motor function. Speech was evaluated before surgery and 3 to 6 months after surgery with stimulator-off and with stimulator-on, with all participants off anti-parkinsonian medication for 12 hours before evaluation. Evaluators ...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

Depression and Intelligence in Patients with Parkinson's Disease and Deep-Brain Stimulation
; ...bilateral subthalamic nucleus stimulation (STN-DBS). The literature has been contradictory...patients with more education not treated with STN-DBS. Other recently published studies indicate that STN-DBS improves the depression associated with...
Speech in Parkinson's disease following subthalamic nucleus deep brain stimulation: preliminary results.
; ...stimulation of the subthalamic nucleus (STN-DBS) is an effective treatment for the improvement...This study aims to compare the effects of STN-DBS versus the effects of medical (drug) treatment...surgical treatment (N = 8) with bilateral STN-DBS or medical treatment (N = 8). Both ...
Brain Networks Underlying the Clinical Effects of Long-Term Subthalamic Stimulation for Parkinson's Disease: A 4-Year Follow-up Study with rCBF SPECT
; ...long term. Methods: Ten PD patients with STN-DBS underwent 3 rCBF SPECT studies at rest-on...during further follow-up. The effect of STN-DBS from the pre- to the postoperative condition...term, as well as in the short term, the STN-DBS achieves its therapeutic benefit by restoring...
High-frequency stimulation of the subthalamic nucleus for the treatment of Parkinson's disease--a team perspective.
; ...subcortical subthalamic nucleus (STN). Over the last 5 years STN DBS has gained acceptance and become the neurosurgical treatment...reviews the preoperative and immediate postoperative aspects of STN DBS and reports on our experiences with this technique. Seventy...
Bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease: results of six patients.
; ...stimulators as a treatment for their PD. It also reviews PD, the limitations of medication management, and literature pertaining to STN DBS for advanced PD. The U.S. Food and Drug Administration (FDA) approved use of a DBS system by Medtronic, Inc., of Minneapolis...
Simulating brain activity in Parkinson's patients.(MEDICAL DEVICE DESIGN)
; ...population, while decreasing the time necessary to successfully implant and parameterize each patient. Model of Subthalamic Nucleus (STN) DBS: A) DBS systems are permanently implanted with a pulse generator in the chest and a four contact electrode stereotactically...
High-Frequency Oscillations in Somatosensory System
; ...generator for two repetitive spikes at around P13/14 of median nerve SEP.4 The direct recording from the subthalamic nucleus (STN) DBS electrodes indicated that a part of HFOs came from brainstem,8,15 and this HFO is made with a volume conduction from the medial...