FDA warns ibuprofen may block aspirin's cardioprotection.(Food and Drug Administration)

Family Practice News | October 15, 2006| | Copyright

Concomitant use of low-dose aspirin and ibuprofen may interfere with aspirin's antiplatelet effects, possibly attenuating its cardioprotective benefits, according to a recent statement by the Food and Drug Administration's arm responsible for compiling adverse drug events.

"Platelet function tests suggest there is a pharmacodynamic interaction between 400 mg of ibuprofen and low-dose aspirin when they are dosed concomitantly," the FDA wrote in a statement posted on its MedWatch Web site in September.

Experts stress, however, that virtually all nonsteroidal ...

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