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Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.(Recently Published Abstracts)(Author abstract)
From:
Alternative Medicine Review
| Date:
September 1, 2006| Author:
Brennan, L.; Flatt, P.R.; Patterson, S.
| COPYRIGHT 2006 Thorne Research Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.Copyright information
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Patterson S, Flatt PR, Brennan L, et al. J Endocrinol 2006;189:301-310.
Elevated plasma homocysteine has been reported in individuals with diseases of the metabolic syndrome including vascular disease and insulin resistance. As homocysteine exerts detrimental effects on endothelial and neuronal cells, this study investigated effects of acute homocysteine exposure on beta-cell function and insulin secretion using clonal BRIN-BD11 beta-cells. Acute insulin release studies ...
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