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TEXTAL: crystallographic protein model building using AI and pattern recognition.(artificial intelligence)
From:
AI Magazine
| Date:
September 22, 2006| Author:
Gopal, Kreshna; Ioerger, Thomas R.; McKee, Erik W.; Pai, Reetal; Romo, Tod D.; Sacchettini, James C.; Smith, Jacob N.
| COPYRIGHT 2006 American Association for Artificial Intelligence. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.Copyright information
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TEXTAL is a computer program that automatically-interprets electron density maps to determine the atomic structures of proteins through X-ray crystallography. Electron density maps are traditionally interpreted by visually fitting atoms into density patterns. This manual process can be time-consuming and error prone, even for expert crystallographers. Noise in the data and limited resolution make map interpretation challenging. To automate the process, TEXTAL employs a variety of AI and pat...
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