Predominance of ancestral lineages of Mycobacterium tuberculosis in India.(RESEARCH)
From: Emerging Infectious Diseases
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Date: 9/1/2006
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Author: Ahmed, Niyaz; Chauhan, Devendra S.; Gutierrez, M. Cristina; Hasnain, Seyed E.; Katoch, Vishwa M.; Locht, Camille; Narayanan, Sujatha; Supply, Philip; Vincent, Veronique; Willery, Eve
Although India has the highest prevalence of tuberculosis (TB) worldwide, the genetic diversity of Mycobacterium tuberculosis in India is largely unknown. A collection of 91 isolates originating from 12 different regions spread across the country were analyzed by genotyping using 21 loci with variable-number tandem repeats (VNTRs), by spoligotyping, by principal genetic grouping (PGG), and by deletion analysis of M. tuberculosis--specific deletion region 1. The isolates showed highly ...
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