Cell death in Porifera: molecular players in the game of apoptotic cell death in living fossils (1).

Canadian Journal of Zoology | February 1, 2006| | Copyright

Abstract: Apoptosis represents the morphological manifestation of programmed cell death and, paradoxically at first sight, it is a prerequisite for metazoan life. Thus, apoptosis is responsible for the demise of cells during many physiological processes. It is also accountable for the death of cells following exposure to countless stimuli. Therefore, it is obvious that apoptosis must be regulated by a complex network of various molecular signaling pathways. Research during the past 20 years has led to the identification of major functional groups of molecules involved in ...

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