Scientists find transcription by committee. (genetic transcription mechanisms)

From: Science News | Date: April 2, 1994| Author: Pennisi, Elizabeth | Copyright information

Anyone curious about how embryos develop, how cancers arise, or even how cells function from day to day must wonder about the transcription of genes. Organisms store the construction plans for proteins in genes. Enzymes called RNA polymerases then retrieve those plans by creating an RNA molecule that matches a particular gene's DNA. The transcribed RNA relays the specifics of the plans to ribosomes, giant cellular complexes that make proteins.

But RNA polymerases do not ...

Related newspaper, magazine, and journal articles from HighBeam Research

Scientists find transcription by committee. (genetic transcription mechanisms)
Science News ; ... data indicate that SRB proteins run this molecular committee - or are even necessary for it to do its work, Sayre told SCIENCE NEWS. Unpublished work by Roger D. Kornberg and his colleagues at Stanford University School of Medicine suggests that other proteins ...
Pretty in pictures: details of molecular machinery gain Nobel.(Roger D. Kornberg )
Science News ; In yeast, the enzyme that transcribes the protein-making instructions encoded in DNA consists of roughly 30,000 atoms. Five years ago, Roger D. Kornberg published a solo portrait and an action shot of this molecular machinery in atomic detail. Last week, Kornberg, of the Stanford University School
Functional analysis to two maize cDNAs encoding T7-like RNA polymerases
Plant Cell ; We have characterized two maize cDNAs, rpoTm and rpoTp, that encode putative T7-like RNA polymerases. In vivo cellular localization experiments using transient expression of the green fluorescent protein suggest that their encoded proteins are targeted exclusively to mitochondria and plastids,
The General Transcription Machinery and General Cofactors
Critical Reviews in Biochemistry and Molecular Biology ; ABSTRACT In eukaryotes, the core promoter serves as a platform for the assembly of transcription preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (pol II), which function collectively to specify the transcription start site. PIC formation
Researchers discover new antibiotic class
DVM ; COLUMBUS-Researchers have found that a promising new class of antibacterial chemicals inhibits one of the most fundamental processes of life; a cell's ability to express genetic material. Knowing exactly how these chemicals keep bacterial cells in check can help scientists make more effective