Transdermal MAOI for depression.(monoamine oxidase inhibitor)(Drug overview)(Clinical report)

Clinical Advisor | July 1, 2006 | Copyright

Product: EMSAM

Companies: Bristol-Myers Squibb and Somerset Pharmaceuticals

Pharmacologic class: Antidepressant (monoamine oxidase inhibitor [MAOI])

Active ingredient: Selegiline 6 mg/24 hrs, 9 mg/24 hrs, 12 mg/24 hrs; transdermal patch.

Indication: Major depressive disorder.

Pharmacology: EMSAM is a matrix-type transdermal patch that is designed to deliver selegiline, an MAOI, continuously over a 24-hour period. Transdermal dosing results in higher exposure to selegiline and lower exposure to metabolites compared to oral dosing, ...

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