Pugnacious mice lack serotonin receptor. (serotonin's action on receptor 5HT1b reduces aggression in mice) (Brief Article)

From: Science News | Date: November 27, 1993| Author: | Copyright information

Disturbances in serotonin's complex web of action have been blamed for many disorders, including migranes, depression, and schizophrenia. As researchers discover more types of receptor molecules for his neurotransmitter--14 are currently known--scientists are gaining greater insights into how a single transmitter can be involved in myraid functions.

Now, researchers say they have new evidence that serotonin's action on one of these receptors, called 5HT1b, helps dampen aggression. The absence of that receptor leads to increased aggressiveness in mice, reports Rene Hen of ...

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