Critical issues on Graves' ophthalmopathy.(AUTOIMMUNE DISEASE)(Cover story) From: Medical Laboratory Observer | Date: May 1, 2006| Author: | COPYRIGHT 2006 Nelson Publishing. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

Graves' ophthalmopathy (GO) is an inflammatory process that affects tissues of the orbit in patients with Graves' disease (GD) and, more rarely, with Hashimoto's thyroiditis. It is the most frequent extrathyroidal manifestation of Graves' disease. GO is a disfiguring disease that impairs, even in its milder forms, the quality of life of affected patients. It is clinically significant in 50% of patients and severe in 3% to 5%. Approximately 50% of patients with GD do not have clinically relevant ocular involvement, although sub-clinical abnormalities can be shown in many of them by ...

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