Aricept setback in vascular dementia trials.(Disease/Disorder overview)(Brief article)

From: Healthy Years | Date: May 1, 2006 | Copyright information

Eleven of 648 patients died recently while taking Aricept in a phase-three trial of the drug to investigate its use to treat vascular dementia. Aricept has been used for about a decade to counteract mild to moderate Alzheimer's disease; this trial by the Eisai company, makers of the drug, was part of the approval process to market the drug in the U.S. for vascular dementia, which is caused ...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

Eleven deaths reported in donepezil vascular dementia trial.(Neuropsychiatric Medicine)
; ...in a trial of the drug for the treatment of vascular dementia, according to preliminary...Eisai Co. Ltd., the drug's maker. None of...only people with vascular dementia (VaD), who had no...of patients with vascular dementia. However, the mortality...of the most recent ...
Company reports 11 deaths in Aricept trial.
; ...in a trial of the drug for the treatment of vascular dementia, according to preliminary...Eisai Co. Ltd., the drug's maker. None of...only people with vascular dementia (VaD), who had no...of patients with vascular dementia. However, the mortality...of the most recent ...
Donepezil may cut death risk in severe AD by 50%.(Geriatric Psychiatry)(treating Alzheimer's disease )
; ...patients with vascular dementia, Dr. Lon Schneider...looking at this drug more carefully...variability among the vascular dementia trials indicates...three times among vascular dementia patients taking the drug, which should...not approved for vascular ...
Alzheimer's mortality declines with donepezil.(Clinical Rounds)(drug therapy)
; ...but the same drug may be dangerous...patients with vascular dementia, Dr. Lon Schneider...times among vascular dementia patients taking the drug, which should...for neither vascular dementia nor severe...supplemental new drug application...
A healthy body, a healthy mind.
; ...mental ability - the disease called vascular dementia - can be delayed. Dr. Desmond, a neurology...person can experience or witness. Vascular dementia refers to an incurable condition characterized...disease. However, it's now thought that vascular dementia often is present in ...
11 DIE IN ALZHEIMER'S DRUG TRIAL.(News)
; ...while taking the Alzheimer's drug Aricept in a clinical trial testing the drug as a treatment for vascular dementia, a company official said...mortality between those on the drug and those on a placebo was...which jointly markets the drug in the United States with...our safety ...
Stroke history raises risk of vascular dementia.(care and treatment)
; ...nearly 20-fold increase in risk for vascular dementia in a univariate, retrospective, case-contr...Fourth International Congress on Vascular Dementia. Among 205 people with vascular dementia and their control cases, those with...
SPECT and vascular dementia
; ...blood flow (CBF) in patients with vascular dementia. In a study published in the February...included 18 patients with diagnoses of vascular dementia (based on imaging and neuropsychological...853 +/- 0.062 (mean +/- SD) in the vascular dementia and control groups, respectively...
Donepezil in the treatment of vascular dementia.(Cochrane Briefs)
; ...donepezil effective in the treatment of vascular dementia? Evidence-Based Answer Donepezil...in patients with mild to moderate vascular dementia and generally is well tolerated...called multi-infarct dementia or vascular dementia ). Both studies were randomized...
New Alzheimer's drug is first therapy to show efficacy in vascular dementia
; ...first evidence suggesting that drug therapy may improve cognition...cerebrovascular disease. The drug is galantamine hydrobromide...inadequate or incomplete treatment." Vascular dementia, the most common type of dementia...10% rate in studies of the drug for Alzheimer's disease. The...