The vanilloid receptor as a putative target of diverse chemicals in multiple chemical sensitivity. Archives of Environmental Health | July 1, 2004| | COPYRIGHT 2004 Heldref Publications. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information) Copyright

THE ORIGIN of this article was an interchange between the 2 authors of this study at the 2003 Chemical Injury Information Network professional meeting at Fairfax, Virginia, during October 3-5, 2003. One of the authors (MLP) presented extensive evidence (1-3) that supported the view that excessive levels of nitric oxide and its oxidant product peroxynitrite, as well as excessive activity of N-methyl-D-aspartate (NMDA) receptors in the brain, are centrally involved in the etiology of multiple chemical sensitivity (MCS). The remaining author (JHA) presented evidence that the ...

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