Vitamin D3 more potent than vitamin D2.(comparative analysis)

Townsend Letter for Doctors and Patients | October 1, 2005| | Copyright

Twenty healthy male volunteers were randomly assigned to receive a single 50,000-IU dose of either vitamin D2 (ergocalciferol) or vitamin D3 (cholecalciferol). Similar increases were seen in the serum concentration of the administered vitamins, indicating equivalent absorption. Both treatments also produced similar initial increases in serum 25-hydroxyvitamin D (250HD) concentrations (the assay measured both 250HD2 and 250HD3) over the first 3 days. However, 250HD levels continued to rise in the vitamin D3 group, peaking at 14 days, whereas 250HD levels fell rapidly in the ...

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