 "Chicago Tribune (Chicago, IL)")
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The Coney story: How Detroit went to the dog.(American Coney Island )(Company Profile)
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Byline: Alan Solomon
DETROIT _ It is 4:18 a.m. The bars have been closed since 2.
At this bleak hour after another long Motor City Saturday night, it is quiet in the all-night American Coney Island on Lafayette Boulevard. In the restaurant: a man accompanied by two astounding women; another man, seated alone, wearing sandals, white Bermudas, a black polo and a haircut that probably cost more than renting either of the astounding women; and a bedraggled man with a defeated look that suggests he has nowhere else to go.
The bedraggled man is nursing a ...
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Aldosterone Receptor Antagonists in the Medical Management of Chronic Heart Failure
Magazine article from: Mayo Clinic Proceedings
; The benefits of aldosterone receptor antagonists (spironolactone...proposed mechanisms of action of aldosterone antagonists are (1) inhibition...Like many hormone receptors, the aldosterone receptor can be either nuclear or...
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Aldosterone antagonism: New insights and clinical implications for heart failure and hypertension. (Highlights of a Symposium & Roundtable).
Magazine article from: Internal Medicine News
; ...in our understanding of the role that aldosterone plays in cardiorenal disease, and with...understanding of the important role aldosterone receptor antagonists may have in treating...there is tantalizing evidence that an aldosterone receptor antagonist approach will become...
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Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial [Na.sup.+] channel [alpha].(Research article)
Magazine article from: Journal of Clinical Investigation
; Aldosterone plays a major role in the regulation...cardiovascular and renal diseases. Many aldosterone-regulated genes--including that...as the release of this repression by aldosterone treatment. Here we provide evidence...
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Does the aldosterone: renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.(Study protocol)
Magazine article from: BMC Cardiovascular Disorders
; ...antihypertensive control would be to target aldosterone antagonists towards patients in whom...characterised by excessive excretion of aldosterone with concomitant suppression of renin...with hypertension. However, neither aldosterone excretion nor plasma renin activity...
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Validity of the aldosterone-renin ratio used to screen for primary aldosteronism
Magazine article from: Mayo Clinic Proceedings
; ...whether the calculated ratio of plasma aldosterone concentration (PAC) to plasma renin...independent measure of circulating aldosterone that is suitable to judge whether PAC...d). Results: The variation in the aldosterone-renin ratio was strongly and inversely...
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Non-genomic effects of aldosterone on intracellular ion regulation and cell volume in rat ventricular myocytes.
Magazine article from: Canadian Journal of Physiology and Pharmacology
; Abstract: Aldosterone has non-genomic effects that express...However, it is still undefined whether aldosterone actually alters intracellular ion...clarify the non-genomic effects of aldosterone, we measured [[[Na.sup...
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Automated Chemiluminescence-Immunoassay for Aldosterone during Dynamic Testing: Comparison to Radioimmunoassays with and without Extraction Steps
Magazine article from: Clinical Chemistry
; Background: Measurements of aldosterone have become more common since...sampling. In all blood samples, aldosterone concentration was measured by...available RIAs without extraction (Aldosterone Maia, Adaltis; Active Aldosterone...
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Cardiovascular benefits of aldosterone receptor antagonists
Magazine article from: Climacteric
; ...in addition to the classic effects of aldosterone on sodium retention, blood volume, blood pressure and potassium homeostasis, aldosterone is involved in fibrotic end-organ...myocardial infarction by the addition of an aldosterone receptor antagonist to standard therapy...
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Aldosterone is relevant for determination of left ventricular mass.
Newspaper article from: Heart Disease Weekly
; ...NewsRx.com & NewsRx.net) -- Aldosterone is relevant for determination of left...experimental studies, the importance of aldosterone for the development of left ventricular...mode echocardiography), urinary aldosterone concentration, and the response of...
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Plasma Aldosterone Assays: Comparison between Chemiluminescence-Based and RIA Methods
Magazine article from: Clinical Chemistry
; To the Editor: Measurement of plasma aldosterone is increasingly required in clinical practice because...alternatives to traditional RIAs for hormones such as aldosterone. We compared aldosterone results obtained with a new CL method (Nichols...
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