Parental chemical exposures and ras mutations in children.(Headliners: Chemical Exposures and Childhood Leukemia)

Environmental Health Perspectives | October 1, 2004| | Copyright

Shu xo, Perentesis JP, Wen w, Buckley JD, Boyle E, Ross JA, Robison LL; Children's Oncology Group. 2004. Parental exposure to medications and hydrocarbons and ras mutations in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. Cancer Epidemiol Biomarkers Prey 13(7):1230-1235.

A variety of carcinogens have been shown to induce ras mutations in animal and human tumor models, and ras proto-oncogene mutations have been implicated in the development of many malignancies including pancreatic and breast cancers. However, few data exist ...

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