Treatment of nevirapine-associated DRESS syndrome with intravenous immune globulin (IVIG).(CASE REPORTS)

From: Journal of Drugs in Dermatology | Date: July 1, 2005| Author: Fields, Katherine S.; Petersen, Marta J.; Chiao, Elizabeth; Tristani-Firouzi, Payam | Copyright information

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an adverse drug reaction most commonly associated with aromatic antiepileptic agents. It is characterized by the triad of skin eruption, fever, and systemic involvement, with the latter usually manifesting as hepatitis and lymphadenopathy. (1) Mortality is primarily due to hepatic failure and can be as high as 10%. (2) Formerly referred to by names such as Dilantin hypersensitivity syndrome an...

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