Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance.(RESEARCH)

From: Emerging Infectious Diseases | Date: June 1, 2005| Author: Brown, Steven D.; Farrell, David J.; Jenkins, Stephen G.; Klugman, Keith P.; Lavin, Bruce S.; Patel, Manish | Copyright information

Streptococcus pneumoniae isolates (N = 31,001) were collected from patients with community-acquired respiratory tract infections during the PROTEKT US surveillance study (2000-2003). While the macrolide (erythromycin) resistance rate remained stable at [approximately equal to] 29%, the prevalence of resistant isolates containing both erm(B) and mef(A) increased from 9.7% in year 1 to 16.4% in year 3, with substantial regional variability. Almost all (99.2%) dual erm(B)+mef(A) macro...

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