Inhalation toxicity of brevetoxin 3 in rats exposed for twenty-two days.(Brevetoxins: Mini-Monograph)

From: Environmental Health Perspectives | Date: May 1, 2005| Author: Benson, Janet M.; Hahn, Fletcher F.; March, Thomas H.; McDonald, Jacob D.; Gomez, Andrea P.; Sopori, Mohan J.; Bourdelais, Andrea J.; Naar, Jerome; Zaias, Julia; Bossart, Gregory D.; Baden, Daniel G. | Copyright information

Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis. Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf. This study assessed possible adverse health effects associated with inhalation exposure to brevetoxin 3, one of the major brevetoxins produced by K. brevis and present in aerosols collected along beaches affected by red tide. Male F344 rats were exposed to brevetoxin 3 at 0, 37,...

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