LOOKING FOR SEROTONIN? SSRIS ARE SELECTIVE, BUT AFFECTED NEURONS ARE NOT.(Selective serotonin reuptake inhibitors)

BIOWORLD Today | April 26, 2005| | Copyright

Byline: Anette Breindl, Science Editor

Among the mysterious aspects of selective serotonin reuptake inhibitors, the newest class of antidepressants, is that they take hours to achieve their cellular effect - increased brain levels of serotonin - but days to weeks to make patients feel better.

In the April 7, 2005, issue of Neuron, researchers from the Baylor College of Medicine in Houston reported results that could explain the reason for the antidepressants' delayed effects. They also provided evidence that the whole concept of a "dopaminergic" ...

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