Focus on: biologics that affect therapeutic agents in dermatology.

From: Journal of Drugs in Dermatology | Date: March 1, 2005| Author: Gaspari, Anthony A.; Saripalli, Yamini V. | Copyright information

Abstract

Tumor necrosis factor (TNF)-[alpha] is one of the oldest known cytokines in human physiology. It is involved in both normal and pathologic states. Virtually every cell and organ in the body are affected by TNF-[alpha]. (1) Though TNF-[alpha] is usually involved in inflammation as a normal host defense response, when overproduced, it can become pathologic and affect almost every organ system. In this article, we address the role of TNF-[alpha] in diseases such as...

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